|
|
|
|
SDS-PAGE - QPRT protein (ab40583)
(enlarge)
|
|
|
|
|
Product Name
|
QPRT protein (T7 Tag)
|
|
Product type
|
Proteins and Peptides
|
|
Peptide
|
Recombinant full length protein (Human) fused to T7-Tag (N-terminal).
|
|
Tested applications
(see key)
|
MS, SDS-PAGE
|
|
Application notes
(see key)
|
Recommended dilutions
MS: Use at an assay dependent dilution.
SDS-PAGE: Use at an assay dependent dilution.
This peptide can be used with studies using ab37515.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Research areas
|
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Huntington's disease
|
|
Relevance
|
QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease and Huntington's disease.
|
|
|
|
|
Purity
|
>95% by SDS-PAGE
|
|
Storage buffer
|
Preservative: 0.002% Sodium Azide
Constituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8.0 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
0.200 mg/ml
|
|
Storage instructions
|
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
|
|
Expression system
|
E. coli
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this QPRT protein (T7 Tag) is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
|
See below for QPRT protein (T7 Tag) images, references, products related to ab40583 and other tools.
|
| |
QPRT protein (T7 Tag) images:
|
 SDS-PAGE - QPRT protein (ab40583)
ab40583 recombinant protein, 4-20% SDS gradient gel with coomassie blue staining. Observed size 31 kDa.
|
| |
| |
|
Search PubMed (MEDLINE) for references to QPRT
|
| |
QPRT protein (T7 Tag) - more information
|
Customer reviews (feedback) regarding QPRT protein (T7 Tag) |
Customer FAQs regarding QPRT protein (T7 Tag) |
Protocols for QPRT protein (T7 Tag) |
Price and availability of products related to QPRT protein (T7 Tag) |
| |
QPRT protein (T7 Tag) - related products:
|
|
|
| |
QPRT protein (T7 Tag) - other tools:
|
Contact Abcam with a Technical Enquiry about QPRT protein (T7 Tag) |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
