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AbcamBiochemicals (Asc-737)

Quetiapine hemifumarate (ab120737)

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Overview

  • Product nameQuetiapine hemifumarate
  • Description
    D2 and 5-HT2 antagonist. Antipsychotic.
  • Biological descriptionD2 and 5-HT2 antagonist. IC50 values (nM) are 329 (D2), 1243 (D1), 148 (5-HT2), 720 (5-HT1A), 90 (α1), 270 (α2), muscarinic (>10,000) and benzodiazepine (>10,000). Antipsychotic. Centrally active following oral administration.
  • Purity> 99%

    • Properties

  • Chemical name2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
  • Molecular Weight441.54
  • Chemical structureChemical Structure
  • Molecular formulaC21H25N3O2S.0.5C4H4O4
  • CAS Number111974-72-2
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • Source

    Synthetic

  • Research Areas

    • References for Quetiapine hemifumarate (ab120737)

    This product has been referenced in:
    • King DJ  et al. A comparison of bd and tid dose regimens of quetiapine (Seroquel) in the treatment of schizophrenia. Psychopharmacology (Berl) 137:139-46 (1998). Read more (PubMed: 9630000) »
    • Saller CF & Salama AI Seroquel: biochemical profile of a potential atypical antipsychotic. Psychopharmacology (Berl) 112:285-92 (1993). Read more (PubMed: 7871032) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"