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Products:Neuroscience >> Neurotransmission >> Secretory Vesicles >> Rabs
Overview
Product name
Anti-RAB23 antibody - Carboxyterminal end
See all RAB23 products (3) ...
Description
Rabbit polyclonal to RAB23 - Carboxyterminal end
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
KLH conjugated synthetic peptide selected from the C-terminal region of human RAB23.
Positive control
293 cell lysates transfected with the RAB23 gene.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Stem Cells >> Signaling Pathways >> Hedgehog >> Surface Molecules
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Regulation
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> GTP
Neuroscience >> Neurotransmission >> Secretory Vesicles >> Rabs
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Western blot - RAB23 antibody - Carboxyterminal end (ab63140)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab63140 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/50 - 1/100.Detects a band of approximately 30 kDa (predicted molecular weight: 27 kDa).
ELISA
ELISA: 1/1000ELISA: 1/1000
Target
Involvement in disease
Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2) [MIM:201000]. A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects.
Sequence similarities
Belongs to the small GTPase superfamily. Rab family.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionQ9ULC3
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- DKFZp781H0695 antibody
- HSPC137 antibody
- MGC8900 antibody
see all
Database links
- Entrez Gene: 51715 Human
- Omim: 606144 Human
- SwissProt: Q9ULC3 Human
- Unigene: 555016 Human
Anti-RAB23 antibody - Carboxyterminal end images:
Western blot - RAB23 antibody - Carboxyterminal end (ab63140)
All lanes : Anti-RAB23 antibody - Carboxyterminal end (ab63140) at 1/50 dilution
Lane 1 : 293 cell lysates untransfected
Lane 2 : 293 cell lysates transiently transfected with the RAB23 gene
Lysates/proteins at 2 µg per lane.
Predicted band size : 27 kDa
Observed band size : 30 kDa (why is the actual band size different from the predicted?)
Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
References for Anti-RAB23 antibody - Carboxyterminal end (ab63140)
ab63140 has not yet been referenced specifically in any publications.
Publishing research using ab63140? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"