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Products:Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ubiquitin E2s and E3s >> SCF Complex E3 Ligase
Overview
Product name
Anti-RAB40C antibody
See all RAB40C products (2) ...
Description
Mouse polyclonal to RAB40C
Specificity
ab67695 is reactive against mammalian transfected lysate.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length Human RAB40C protein
Positive control
Transfected 293T cells.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ubiquitin E2s and E3s >> SCF Complex E3 Ligase
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Western blot - RAB40C antibody (ab67695)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab67695 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: 1/500 - 1/1000. Detects a band of approximately 31 kDa (predicted molecular weight: 31 kDa).
Detection Antibody Pair
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Pathway
Protein modification; protein ubiquitination.
Sequence similarities
Belongs to the small GTPase superfamily. Rab family.
Contains 1 SOCS box domain.
Domain
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionQ96S21
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Rar like protein antibody
- Ras like protein family member 8C antibody
- SOCS box containing protein RAR3 antibody
see all
Database links
- Entrez Gene: 57799 Human
- SwissProt: Q96S21 Human
- Unigene: 459630 Human
Anti-RAB40C antibody images:
Western blot - RAB40C antibody (ab67695)
All lanes : Anti-RAB40C antibody (ab67695) at 1/500 dilution
Lane 1 : RAB40C transfected 293T cells lysate
Lane 2 : non transfected lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 31 kDa
Observed band size : 31 kDa
References for Anti-RAB40C antibody (ab67695)
ab67695 has not yet been referenced specifically in any publications.
Publishing research using ab67695? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"