|
|
|
|
|
Product Name
|
RAB7 antibody
|
| |
See all RAB7 antibodies (5)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to RAB7
|
|
Immunogen
|
Synthetic peptide from the internal part of human RAB7 conjugated to an immunogenic carrier protein.
|
|
Reacts with
|
Hu, Ms
|
|
Predicted to react
(species key)
|
Xl
(Due to sequence homology)
|
|
Specificity
|
ab74906 is specific for RAB7.
|
|
Tested applications
(see key)
|
IHC-Fr, IHC-P, WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
IHC-P: 1/300 - 1/2000. Antigen retrieval recommended.
IHC-Fr: 1/300 - 1/2000.
WB: 1/300 - 1/2000. Predicted molecular weight: 23 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Endosome; late endosome. Lysosome. Cytoplasmic vesicle; phagosome. Melanosome.
|
|
Research areas
|
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Regulation
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Lysosome
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Endosome
|
|
Relevance
|
Members of the RAB family of RAS related GTP binding proteins are important regulators of vesicular transport and are located in specific intracellular compartments. RAB7 has been localized to late endosomes and shown to be important in the late endocytic pathway. In addition, it has been shown to have a fundamental role in the cellular vacuolation induced by the cytotoxin VacA of Helicobacter pylori.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Whole antiserum
|
|
Storage buffer
|
Preservative: None
Constituents: PBS, Whole serum
|
|
Form
|
Liquid
|
|
Concentration
|
Concentration not determined - why is this?
|
|
Storage instructions
|
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RAB7 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to RAB7
|
| |
RAB7 antibody - more information
|
Customer reviews (feedback) regarding RAB7 antibody |
Customer FAQs regarding RAB7 antibody |
Protocols for RAB7 antibody |
Price and availability of products related to RAB7 antibody |
| |
RAB7 antibody - related products:
|
|
|
| |
RAB7 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about RAB7 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
