Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Related products
- Secondary antibodies
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Anti-RAP1A + RAP1B antibody
See all RAP1A + RAP1B products (3) ...
Description
Rabbit polyclonal to RAP1A + RAP1B
Tested applications
WB, Flow Cyt, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues near the N-terminus of human RAP1A + RAP1B.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity
Whole antiserum
Purification notes
This antibody is not purified.
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Epigenetics and Nuclear Signaling >> Chromosome Structure >> Telomeres
Applications
Show applications key
Our Abpromise guarantee covers the use of ab40814 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000 - 1/5000. Predicted molecular weight: 21 kDa.
Flow Cyt
Flow Cyt: 1/20.Flow Cyt: 1/20.
IHC-P: 1/50 - 1/100.
Target
Relevance
RAP1A and RAP1B belong to a family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Human RAP1B is 95% identical to RAP1A. RAP1A and B are proposed to regulate Ras-mediated signalling and may also be involved in the regulation of integrin-mediated cell adhesion, although the mechanism of regulation is not known.
Cellular localization
Cell Membrane; Attached to the membrane by a lipid anchor
Alternative names
- C21KG antibody
- G 22K antibody
- GTP binding protein smg p21A antibody
see all
Database links
- Entrez Gene: 5906 Human
- Entrez Gene: 5908 Human
- Entrez Gene: 109905 Mouse
- Entrez Gene: 215449 Mouse
- Entrez Gene: 171337 Rat
- Entrez Gene: 295347 Rat
- Omim: 179520 Human
- Omim: RAP1B Human
see all
Anti-RAP1A + RAP1B antibody images:
Western blot - RAP1A + RAP1B antibody (ab40814)
Anti-RAP1A + RAP1B antibody (ab40814) at 1/5000 dilution + C6 cell lysate
Predicted band size : 21 kDa
Observed band size : 21 kDa
Immunohistochemistry (Paraffin-embedded sections) - RAP1A + RAP1B antibody (ab40814)
Ab40814 staining human RAP1A + RAP1B in human cervical carcinoma by immunohistochemistry using paraffin embedded tissue.
References for Anti-RAP1A + RAP1B antibody (ab40814)
ab40814 has not yet been referenced specifically in any publications.
Publishing research using ab40814? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"