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Anti-RBP4 antibody (ab57620)

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Overview

Product name

Anti-RBP4 antibody
See all RBP4 products (11) ...

Description

Mouse monoclonal to RBP4

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant full length protein, corresponding to amino acids 19-202 of Human RBP4

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG1

Light chain type

kappa

Research areas

Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Vitamins / Minerals
Cardiovascular >> Blood >> Serum Proteins

  • Western blot - RBP4 antibody (ab57620)Western blot - RBP4 antibody (ab57620) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab57620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

Involvement in disease

Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

Sequence similarities

Belongs to the calycin superfamily. Lipocalin family.

Cellular localization

Secreted.

Target information above from: UniProt accessionP02753 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • OTTHUMP00000020114 antibody
  • OTTHUMP00000020115 antibody
  • OTTHUMP00000020116 antibody
  • Plasma retinol binding protein 4 antibody
  • Plasma retinol-binding protein antibody
  • Plasma retinol-binding protein(1-176) antibody
  • PRBP antibody
  • PRO2222 antibody
  • RBP antibody
  • RBP4 antibody
  • RET4_HUMAN antibody
  • Retinol binding protein 4 antibody
  • Retinol binding protein 4 interstitial antibody
  • Retinol binding protein 4 plasma antibody
see all

Database links

Anti-RBP4 antibody images:

  Western blot - RBP4 antibody (ab57620)

Western blot - RBP4 antibody (ab57620)

RBP4 antibody (ab57620) at 1ug/lane + HepG2 cell lysate at 25ug/lane.

References for Anti-RBP4 antibody (ab57620)

ab57620 has not yet been referenced specifically in any publications.

Publishing research using ab57620? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"