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Products:Cardiovascular >> Blood >> Serum Proteins
Overview
Product name
Anti-RBP4 antibody
See all RBP4 products (11) ...
Description
Mouse monoclonal to RBP4
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 19-202 of Human RBP4
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
lambda
Research areas
Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Vitamins / Minerals
Cardiovascular >> Blood >> Serum Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57622 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 23 kDa.
IHC-P: Use a concentration of 1 µg/ml
Target
Function
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
Involvement in disease
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Sequence similarities
Belongs to the calycin superfamily. Lipocalin family.
Cellular localization
Secreted.
Target information above from: UniProt accessionP02753
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- OTTHUMP00000020114 antibody
- OTTHUMP00000020115 antibody
- OTTHUMP00000020116 antibody
see all
Database links
- Entrez Gene: 5950 Human
- Omim: 180250 Human
- SwissProt: P02753 Human
- SwissProt: Q5VY30 Human
- Unigene: 50223 Human
Anti-RBP4 antibody images:
IHC-P - RBP4 antibody (ab57622)
RBP4 antibody (ab57622) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human pancreas.
Western blot - RBP4 antibody (ab57622)
Predicted band size : 23 kDa
Western blot against tagged recombinant protein immunogen using ab57622 RBP4 antibody at 1ug/ml. Predicted band size of immunogen including a proprietory tag is 46 kDa
References for Anti-RBP4 antibody (ab57622)
ab57622 has not yet been referenced specifically in any publications.
Publishing research using ab57622? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"