RBP4 protein (ab59967)

Product Name 

RBP4 protein

Product type 

Proteins and Peptides

Peptide 

Recombinant full length mature human RBP4, corresponding to amino acids 19-201, 184aa, MW 21kDa.

Tested applications 
(see key)

SDS-PAGE

Application notes 
(see key)

Recommended dilutions
SDS-PAGE: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Vitamins / Minerals
Cardiovascular >> Blood >> Serum Proteins

Relevance 

RBP4 is a specific carrier for retinol in the blood. It is a member of the lipocalin protein family. Under physiological conditions, RBP binds transthyretin (TTR) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The RBP/TTR molar ration provides an indirect way to indicate marginal vitamin A deficiency. RBP4 may also play a role in insulin resistance in diabetes.

Purity 

Size exclusion

Storage buffer 

Preservative: None
Constituents: PBS, pH 7.4 (10mM Phosphate, 137mM NaCl, 2.7mM KCl)

Purification notes 

Purified by using conventional chromatography techniques.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes 

Endotoxin test showed more than 0.5 EU/mg endotoxin level.

Expression system 

E. coli

Sequence 

MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL

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