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Products:Cardiovascular >> Blood >> Serum Proteins
Overview
Product name
RBP4 protein
See all RBP4 products (11) ...
Protein description
Recombinant full length mature human RBP4, corresponding to amino acids 19-201, 184aa, MW 21kDa.
Expression host
E. coli
Properties
Purity
Size exclusion
Purification notes
Purified by using conventional chromatography techniques.
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS, pH 7.4 (10mM Phosphate, 137mM NaCl, 2.7mM KCl)
Concentration
Concentration information loading...
Additional notes
Endotoxin test showed more than 0.5 EU/mg endotoxin level.
Sequence notes
MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL
Research areas
Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Vitamins / Minerals
Cardiovascular >> Blood >> Serum Proteins
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SDS-PAGE - RBP4 protein (ab59967)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab59967 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
Protein info
Function
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
Involvement in disease
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
Sequence similarities
Belongs to the calycin superfamily. Lipocalin family.
Cellular localization
Secreted.
Target information above from: UniProt accessionP02753
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
RBP4 protein images:
References for RBP4 protein (ab59967)
ab59967 has not yet been referenced specifically in any publications.
Publishing research using ab59967? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"