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- Proteins and Peptides
- Secondary antibodies
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Product name
Anti-Rab3C antibody
See all Rab3C products (2) ...
Description
Rabbit polyclonal to Rab3C
Tested applications
WB, IP, IHC-FoFrmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Synthetic peptide: MASAQDARFGQKDSSDQN-C, corresponding to amino acids 9-26 of Rat Rab3C.
MASAQDARFGQKDSSDQN-C
Positive control
AtT20 cells.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
PBS, 1 mg/ml BSA, 0.05% sodium azide
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Regulation
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
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Western blot - Rab3C antibody (ab3336)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab3336 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
IP
IHC-FoFr
Application notes
IHC-FoFr: Use at an assay dependent dilution (PMID 19786578).
IP: Use at an assay dependent concentration.
WB: Use at an assay dependent concentration.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins: synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in co-ordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 3C is found in brain, adrenal gland and pituitary.
Cellular localization
Cell membrane; Lipid-anchor; Cytoplasmic side.
Alternative names
- RAB3C member RAS oncogene family antibody
- Ras-related protein Rab3C antibody
Database links
- Entrez Gene: 67295 Mouse
- SwissProt: Q63482 Mouse
- Unigene: 151600 Mouse
Anti-Rab3C antibody images:
References for Anti-Rab3C antibody (ab3336)
This product has been referenced in:
- Van Keymeulen A et al. Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol 187:91-100 (2009). IHC-FoFr; Mouse.Read more (PubMed: 19786578) »
See 1 publication for this product
Publishing research using ab3336? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"