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Western blot - RDH12 antibody (ab72874)
(enlarge)
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Product Name
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RDH12 antibody
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See all RDH12 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse polyclonal to RDH12
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Immunogen
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Full length human RDH12 protein (NP_689656.1)
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/500 - 1/1000. Predicted molecular weight: 35 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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RDH12-transfected 293T cell lysate
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Cellular localization
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Cytoplasmic
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Research areas
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Signal Transduction >> Metabolism >> Vitamins / Minerals
Neuroscience >> Sensory System >> Visual system
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Relevance
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RDH12, also known as retinol dehydrogenase 12 (all-trans/9-cis/11-cis), is an NADPH-dependent retinal reductase. Its highest activity is towards 9-cis and all-trans retinol. RDH12 may be the key enzyme involved in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in the RDH12 gene result in Leber congenital amaurosis type 3 (LCA3). LCA3 affected infants have little or no photoreceptor function.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RDH12 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for RDH12 antibody images, references, products related to ab72874 and other tools.
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RDH12 antibody images:
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 Western blot - RDH12 antibody (ab72874)
All lanes : RDH12 antibody (ab72874) at 1/500 dilution
Lane 1 : RDH12 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Predicted band size : 35 kDa
Observed band size : 35 kDa
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Search PubMed (MEDLINE) for references to RDH12
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RDH12 antibody - more information
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Customer reviews (feedback) regarding RDH12 antibody |
Customer FAQs regarding RDH12 antibody |
Protocols for RDH12 antibody |
Price and availability of products related to RDH12 antibody |
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RDH12 antibody - related products:
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RDH12 antibody - other tools:
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Contact Abcam with a Technical Enquiry about RDH12 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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