|
|
|
|
|
Product Name
|
RECQL5 peptide
|
|
Product type
|
Proteins and Peptides
|
|
Peptide
|
Synthetic peptide derived from within residues 950 to the C-terminus of Human RECQL5.
This peptide was used as an immunogen for ab31609 - RECQL5 antibody.
|
|
Research areas
|
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> Other
|
|
Relevance
|
RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance. RecQL5 is one of five known RecQ homologues in humans, and defects in three of these (BLM, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer. The exact role of ReqL5 is unclear. It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), whereas deleting Recql5 lead to an even higher frequency of SCE. There are three different RecQL5 isoforms - alpha, beta and gamma, produced by alternative splicing.
|
|
|
|
|
Storage buffer
|
Preservative: None
Constituents: 0.001% Tween 20, HEPES, 2mM EDTA, 150mM Sodium chloride
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RECQL5 peptide is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to RECQL5
|
| |
RECQL5 peptide - more information
|
Customer reviews (feedback) regarding RECQL5 peptide |
Customer FAQs regarding RECQL5 peptide |
Protocols for RECQL5 peptide |
Price and availability of products related to RECQL5 peptide |
| |
RECQL5 peptide - related products:
|
|
|
| |
RECQL5 peptide - other tools:
|
Contact Abcam with a Technical Enquiry about RECQL5 peptide |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
