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Products:Immunology >> Secreted Molecules >> Other secreted molecules
Overview
Product name
REG4 protein (His tag)
See all REG4 products (2) ...
Protein description
Recombinant full length REG4 protein (Human) 136 AA, with an N terminal His tag, calculated MW 17.4kDa
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Purification notes
Please filter the product by an appropriate sterile filter before using it in the cell culture.
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 20mM Tris, pH 8
Concentration
Concentration information loading...
Sequence notes
MKHHHHHHAS HMDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
Research areas
Cancer >> Tumor biomarkers >> Other
Immunology >> Secreted Molecules >> Other secreted molecules
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SDS-PAGE - REG4 protein (His tag) (ab63304)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab63304 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 18 kDa.
ELISA: Use at an assay dependent dilution.
Protein info
Function
May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
Tissue specificity
Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
Sequence similarities
Contains 1 C-type lectin domain.
Cellular localization
Secreted.
Target information above from: UniProt accessionQ9BYZ8
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
REG4 protein (His tag) images:
SDS-PAGE - REG4 protein (His tag) (ab63304)
1. MW marker – 14, 21, 31, 45, 66, 97 kDa 2. reduced and heated sample, 5µg/lane 3. non-reduced and non-heated sample, 5µg/lane
References for REG4 protein (His tag) (ab63304)
ab63304 has not yet been referenced specifically in any publications.
Publishing research using ab63304? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"