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IHC-P - RICTOR antibody (ab56578)
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Western blot - RICTOR antibody (ab56578)
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Product Name
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RICTOR antibody
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See all RICTOR antibodies (7)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to RICTOR
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Immunogen
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Recombinant fragment: MAAIGRGRSL KNLRVRGRND SGEENVPLDL TREPSDNLRE ILQNVARLQG VSNMRKLGHL NNFTKLLCDI GHSEEKLGFH YEDIIICLRL ALLNEAKE, corresponding to amino acids 1-99 of Human RICTOR
BLAST 'MAAIGRGRSL KNLRVRGRND SGEENVPLDL TREPSDNLRE ILQNVARLQG VSNMRKLGHL NNFTKLLCDI GHSEEKLGFH YEDIIICLRL ' with  or 
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Reacts with
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Hu
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Tested applications
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic
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Research areas
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Signal Transduction >> Adapters >> Cytoplasmic
Signal Transduction >> Protein Phosphorylation >> pSer / pThr
Cell Biology >> Cell Cycle >> Cell Cycle Inhibitors >> Other
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Relevance
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RICTOR is a component of a protein complex [mTORC2] that integrates nutrient- and growth factor-derived signals to regulate cell growth. Rictor is a key component of mTORC2 which plays an essential role in Akt phosphorylation and signaling.
Deregulation of Akt/protein kinase B (PKB) is implicated in the pathogenesis of cancer and diabetes. Rictor-mTOR may serve as a drug target in tumors that have lost the expression of PTEN, a tumor suppressor that opposes Akt/PKB activation.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2b
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RICTOR antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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RICTOR antibody images:
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 IHC-P - RICTOR antibody (ab56578)
RICTOR antibody (ab56578) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.
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Western blot - RICTOR antibody (ab56578)
Predicted band size : 30 kDa
RICTOR antibody (ab56578) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to RICTOR
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RICTOR antibody - more information
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Customer reviews (feedback) regarding RICTOR antibody |
Customer FAQs regarding RICTOR antibody |
Protocols for RICTOR antibody |
Price and availability of products related to RICTOR antibody |
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RICTOR antibody - other tools:
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Contact Abcam with a Technical Enquiry about RICTOR antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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