RNA Helicase A peptide (ab27786)

Product Name 

RNA Helicase A peptide

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide derived from within residues 100 - 200 of Human RNA Helicase A.


This peptide was used as an immunogen for ab26271 - RNA Helicase A antibody.

Research areas 

Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Nuclear Pore Complex
Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other

Relevance 

RNA Helicase A unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. It functions as a transcriptional activator.

It binds MBD2, HRMT1L2/PRMT1, and RELA. It may act to directly link BRCA1, CREBBP or SMN1 and the RNA polymerase II complex. It can also interact with XRCC5 and with TOP2A in a RNA dependent manner; these interactions may be indirect. Interaction with TOP2A is promoted by UBC9 (referenced from swissprot).

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, HEPES, 2mM EDTA, 150mM Sodium chloride

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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