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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)
(enlarge)


Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)
(enlarge)


Product Name 

RNA polymerase II (phospho S2) antibody

 

See all RNA polymerase II antibodies (13)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to RNA polymerase II (phospho S2)

Immunogen 

Phosphorylated synthetic peptide, which represented a portion of human RNA Polymerase II around serine 2 of the C-terminal repeat YSPTSPS.

Reacts with 
(species key)

Hu, Ms

Tested applications 
(see key)

IHC-P


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/100 - 1/500.
Epitope exposure with citrate buffer will enhance staining.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human Ovarian Carcinoma, Mouse Teratoma.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Transcription >> RNA polymerase
Chromatin and Nuclear Signaling >> Transcription >> Polymerase associated factors >> Pol II Transcription >> Polymerase

Relevance 

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. RNA polymerase II has two physiologically important phosphorylation sites; ser 2 and ser 5. Both sites are found in the heptapeptide repeat YSPTSPS at the C terminal domain.

 

Alternative names RNA polymerase II (phospho S2) antibody (ab84988)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

5430    (Human)
20020    (Mouse)

Omim

    

180660    (Human)

SwissProt

    

P24928    (Human)
P08775    (Mouse)

Unigene

    

270017    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RNA polymerase II (phospho S2) antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for RNA polymerase II (phospho S2) antibody images, references, products related to ab84988 and other tools.

 

RNA polymerase II (phospho S2) antibody images:

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)

ab84988 at 1/250 dilution staining RNA Polymerase II in serial sections of human ovarian carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
Mock phosphatase treated section (left) or calf intestinal phosphatase-treated section (right).

 

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - RNA polymerase II (phospho S2) antibody (ab84988)

ab84988 at 1/250 dilution staining RNA Polymerase II in serial sections of mouse teratoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining. Mock phosphatase treated section (left) or calf intestinal phosphatase-treated section (right).

 
 

Search PubMed (MEDLINE) for references to RNA polymerase II

 

RNA polymerase II (phospho S2) antibody - more information

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RNA polymerase II (phospho S2) antibody - related products:

Products for Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Slides

 

Positive Controls for RNA polymerase II (phospho S2) antibody

ab4879

  

Lung tumor (human): adenocarcinoma tissue slides

ab4892

  

Lung tumor (human): small cell carcinoma tissue slides

ab5129

  

Testis tumor (human): seminoma tissue slides

 

Compatible Secondaries for RNA polymerase II (phospho S2) antibody

ab6564

  

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ab6717

  

FITC antibody

ab6720

  

Biotin antibody

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HRP antibody

ab6722

  

Alkaline Phosphatase antibody

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Texas Red ® antibody

ab7007

  

Phycoerythrin antibody

ab7019

  

Agarose antibody

ab27234

  

10nm Gold antibody

ab27235

  

5nm Gold antibody

ab27236

  

15nm Gold antibody

ab27237

  

20nm Gold antibody

ab27238

  

30nm Gold antibody

ab27239

  

10nm Gold antibody

ab27240

  

5nm Gold antibody

ab31193

  

Duck polyclonal to Rabbit IgG

ab60314

  

Chromeo™ 488 antibody

ab60315

  

Chromeo™ 494 antibody

ab60317

  

Chromeo™ 546 antibody

ab60319

  

Chromeo™ 642 antibody

 

Other RNA polymerase II Antibodies

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RNA polymerase II (phospho S2) antibody - other tools:

Contact Abcam with a Technical Enquiry about RNA polymerase II (phospho S2) antibody

 

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