Anti-RNASE6 antibody (ab121111)
Key features and details
- Rabbit polyclonal to RNASE6
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RNASE6 antibody -
Description
Rabbit polyclonal to RNASE6 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to amino acids 25-144 of Human RNASE6 (Q93091).
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Positive control
- Human Liver tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab121111 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use buffer at pH 6 for antigen retrieval. |
Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval. |
Target
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Function
May have a role in host defense. -
Tissue specificity
Strong expression in lung, followed by heart, placenta, kidney, pancreas, liver, brain and skeletal muscle. Also expressed in monocytes and neutrophils. -
Sequence similarities
Belongs to the pancreatic ribonuclease family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6039 Human
- Omim: 601981 Human
- SwissProt: Q93091 Human
- Unigene: 23262 Human
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Alternative names
- Ribonuclease K6 antibody
- RNAS6_HUMAN antibody
- RNase K6 antibody
- RNASE6 antibody
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab121111 has been referenced in 2 publications.
- Pan R et al. A novel immune cell signature for predicting osteosarcoma prognosis and guiding therapy. Front Immunol 13:1017120 (2022). PubMed: 36189307
- Becknell B et al. Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract. Kidney Int N/A:N/A (2014). PubMed: 25075772