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Product name
Anti-RRAGB antibody
See all RRAGB products (2) ...
Description
Mouse monoclonal to RRAGB
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-347 of Human RRAGB
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Splicing
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> GTP
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Western blot - RRAGB antibody (ab56633)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56633 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Involved in the RCC1/Ran-GTPase pathway. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Cellular localization
Cytoplasm
Alternative names
- GTP-binding protein ragB antibody
- Rag B antibody
- RagB antibody
- Ras-related GTP-binding protein B antibody
Database links
- Entrez Gene: 10325 Human
- Omim: 300725 Human
- SwissProt: Q5VZM2 Human
Anti-RRAGB antibody images:
Western blot - RRAGB antibody (ab56633)
Western blot against tagged recombinant protein immunogen using ab56633 RRAGB antibody at 1ug/ml. Predicted band size of immunogen is 64 kDa
References for Anti-RRAGB antibody (ab56633)
This product has been referenced in:
- Sancak Y et al. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320:1496-501 (2008). WB; Human.Read more (PubMed: 18497260) »
See 1 publication for this product
Publishing research using ab56633? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"