|
|
|
|
Western blot - RRAS antibody (ab57650)
(enlarge)
|
|
|
|
|
Product Name
|
RRAS antibody
|
| |
See all RRAS antibodies (3)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal to RRAS
|
|
Immunogen
|
Recombinant fragment, corresponding to amino acids 109-218 of Human RRAS
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Cell membrane; lipid anchor; cytoplasmic side
|
|
Research areas
|
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
Cell Biology >> Apoptosis >> Intracellular >> Associated Proteins
|
|
Relevance
|
RRAS (Related RAS viral (r-ras) oncogene homolog) is a member of the Ras superfamily of small GTPases which regulate cell proliferation, spreading, migration, apoptosis, and malignant transformation by binding to several protein effectors. RLIP76 (RalBP1) has recently been identified as a novel RRas effector. RLIP76 is required for adhesion induced Rac activation and the resulting cell spreading and migration, as well as for the ability of RRas to enhance these functions. RRAS does not activate MAP kinase pathways and is only weakly oncogenic.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Isotype
|
IgG2b
|
|
Light chain type
|
kappa
|
|
Purity
|
Protein G purified
|
|
Storage buffer
|
Preservative: None
PBS, pH 7.2
|
|
Form
|
Liquid
|
|
Concentration
|
Batch dependent within range: 0.37 - 1.00 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this RRAS antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
RRAS antibody images:
|
 Western blot - RRAS antibody (ab57650)
Predicted band size : 23 kDa
RRAS antibody (ab57650) at 1ug/lane + HeLa cell lysate at 25ug/lane.
|
| |
| |
|
Search PubMed (MEDLINE) for references to RRAS
|
| |
RRAS antibody - more information
|
Customer reviews (feedback) regarding RRAS antibody |
Customer FAQs regarding RRAS antibody |
Protocols for RRAS antibody |
Price and availability of products related to RRAS antibody |
| |
RRAS antibody - other tools:
|
Contact Abcam with a Technical Enquiry about RRAS antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
