Overview

  • Product name
  • Description
    Rabbit polyclonal to RREB1
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 1375-1425 of Human RREB1 (NP_002946.4).

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.
    • Tissue specificity
      Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
    • Sequence similarities
      Belongs to the krueppel C2H2-type zinc-finger protein family.
      Contains 15 C2H2-type zinc fingers.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Nucleus speckle.
    • Information by UniProt
    • Database links
    • Alternative names
      • FINB antibody
      • Finger protein in nuclear bodies antibody
      • Hindsight homolog antibody
      • HNT antibody
      • LZ321 antibody
      • Raf responsive zinc finger protein LZ321 antibody
      • Raf-responsive zinc finger protein LZ321 antibody
      • RAS responsive element binding protein 1 antibody
      • Ras-responsive element-binding protein 1 antibody
      • RREB 1 antibody
      • RREB-1 antibody
      • Rreb1 antibody
      • RREB1_HUMAN antibody
      • Zep 1 antibody
      • Zep-1 antibody
      • Zep1 antibody
      • Zinc finger motif enhancer binding protein 1 antibody
      • Zinc finger motif enhancer-binding protein 1 antibody
      see all

    Images

    • Detection of RREB1 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab113287 at 6 µg/mg lysate for IP. A Rabbit anti-RREB1 antibody which recognizes a downstream epitope was used at 1 µg/ml for subsequent Western blot detection. Lane 2 represents control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.

    References

    ab113287 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab113287.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up