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Product Name 

Rab24 antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to Rab24

Immunogen 

A synthetic peptide as a part of human, rat and mouse Rab24 conjugated to an immunogenic carrier protein.

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

IHC-Fr, IHC-P, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/300 - 1/2000. Perform antigen retrieval before commencing with IHC staining protocol.
IHC-Fr: 1/300 - 1/2000.
WB: 1/300 - 1/2000. Predicted molecular weight: 23 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasm; cytosol. Membrane; Lipid-anchor. Note: Only about 20-25% is recovered in the particulate fraction.

Research areas 

Cancer >> Cancer Metabolism >> Autophagy
Cardiovascular >> Heart >> Autophagy >> APG gene products

Relevance 

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.

 

Rab24 antibody (ab65058)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

53917    (Human)
19336    (Mouse)
361208    (Rat)

Omim

    

612415    (Human)

SwissProt

    

Q969Q5    (Human)
P35290    (Mouse)
Q5BK70    (Rat)

Unigene

    

16258    (Human)
220923    (Mouse)
6295    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: PBS, Whole serum

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Rab24 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to Rab24

 

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