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Anti-Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917)

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Overview

Product name

Anti-Rab3A + Rab3B + Rab3C + Rab3D antibody

Description

Rabbit polyclonal to Rab3A + Rab3B + Rab3C + Rab3D

Tested applications

WBmore details

Cross reactivity

Reacts with

Rat

Predicted to work with

Mouse, Human, Xenopus laevis, Non Human Primates

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat Rab3, conjugated to KLH. The amino acid sequence is not avialble.

Positive control

Rat cortex lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES, pH 7.5

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Signal transduction >> G protein signaling >> Small G proteins >> Ras family
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Ras Family
Neuroscience >> Neurotransmission >> Secretory Vesicles >> Rabs

  • Western blot - Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917)Western blot - Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab42917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/1000Detects a band...Read more →

    WB: 1/1000Detects a band of approximately 27 kDa (predicted molecular weight: 24 kDa).

Target

Relevance

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.

Cellular localization

Cell membrane; lipid-anchor; cytoplasmic side

Alternative names

  • D2 2 antibody
  • Glioblastoma overexpressed antibody
  • GOV antibody
  • RAB16 antibody
  • RAB3A antibody
  • RAB3A member RAS oncogene family antibody
  • RAB3B antibody
  • RAB3B member RAS oncogene family antibody
  • RAB3C antibody
  • RAB3C member RAS oncogene family antibody
  • RAB3D member RAS oncogene family antibody
  • RAD3D antibody
  • Ras related protein Rab 3A antibody
  • Ras related protein Rab 3B antibody
  • Ras related protein Rab 3C antibody
  • Ras related protein Rab 3D antibody
see all

Database links

see all

Anti-Rab3A + Rab3B + Rab3C + Rab3D antibody images:

  Western blot - Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917)

Western blot - Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917)

Anti-Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917) at 1/1000 dilution + 20 ug rat cortex lysate.

Secondary
Goat-anti-rabbit HRP. at 1/15000 dilution

Predicted band size : 24 kDa
Observed band size : 27 kDa (why is the actual band size different from the predicted?)

References for Anti-Rab3A + Rab3B + Rab3C + Rab3D antibody (ab42917)

ab42917 has not yet been referenced specifically in any publications.

Publishing research using ab42917? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"