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Anti-RanBP1 antibody (ab2937)

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Overview

Product name

Anti-RanBP1 antibody
See all RanBP1 products (6) ...

Description

Rabbit polyclonal to RanBP1

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide: MAAAKDTHEDHDTSTENT-C, corresponding to amino acids 1-18 of Human RanBP1.

MAAAKDTHED HDTSTENT-C

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

HeLa cell lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

PBS, 1 mg/ml BSA, 0.05% sodium azide

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Signal Transduction >> Protein Trafficking >> Nuclear Import / Export
Cell Biology >> Cell Cycle >> Cell Division >> Spindle

Applications

Show applications key

Our Abpromise guarantee covers the use of ab2937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • WB

     

Application notes

WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 30 kDa in HeLa cell extract(predicted molecular weight: 24 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

Sequence similarities

Belongs to the RANBP1 family.
Contains 1 RanBD1 domain.

Target information above from: UniProt accessionP43487 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • HTF9A antibody
  • RAN binding protein 1 antibody
  • Ran specific GTPase activating protein antibody
  • Ran-binding protein 1 antibody
  • Ran-specific GTPase-activating protein antibody
  • RANBP1 antibody
  • RANG_HUMAN antibody
see all

Database links

References for Anti-RanBP1 antibody (ab2937)

This product has been referenced in:

  • Schulz Met al. Proteomic analysis of peripheral blood mononuclear cells: selective protein processing observed in patients with rheumatoid arthritis. J Proteome Res 6:3752-9 (2007).Read more (PubMed: 17705417) »

See 1 publication for this product

Publishing research using ab2937? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"