Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MDPETCPCPSGGSCTCADSCKCEGCKCTSCKKSCCSCCPAECEKCAKDCV CKGGEAAEAEAEKCSCCQ
    • Molecular weight
      33 kDa including tags
    • Amino acids
      1 to 68

Specifications

Our Abpromise guarantee covers the use of ab114897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • GIF
    • GIFB
    • GRIF
    • Growth inhibitory factor
    • Metallothionein 3
    • Metallothionein 3 (growth inhibitory factor (neurotrophic))
    • Metallothionein III
    • Metallothionein-3
    • Metallothionein-III
    • Mt 3
    • MT III
    • MT-3
    • MT-III
    • MT3
    • MT3_HUMAN
    • ZnMT3
    see all
  • Function
    Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
  • Tissue specificity
    Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
  • Sequence similarities
    Belongs to the metallothionein superfamily. Type 1 family.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab114897 at approximately 33.11kDa.
    Stained with Coomassie Blue.

     

References

ab114897 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab114897.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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