The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
>95% by SDS-PAGE . ab206786 was purified using conventional chromatography techniques.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4 Constituents: 90% PBS, 10% Glycerol
Collagenase inhibitor, Human
Erythroid Potentiating Activity
Fibroblast collagenase inhibitor
Human Collagenase Inhibitor
Metalloproteinase inhibitor 1
Metalloproteinase inhibitor 1 precursor
TIMP metallopeptidase inhibitor 1
Tissue Inhibitor of Metalloproteinase 1
Tissue inhibitor of metalloproteinases
Tissue inhibitor of metalloproteinases 1
Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
Belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain.
The activity of TIMP1 is dependent on the presence of disulfide bonds.