Recombinant human SCGF beta protein (ab9836)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human SCGF beta protein -
Purity
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
Expression system
Escherichia coli -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Predicted molecular weight
36 kDa
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab9836 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Lyophilized -
Additional notes
The ED50, determined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF, is <7.0ng/ml. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.16% Sodium phosphate, 0.18% Sodium chloride, 0.015% DTT
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionFor lot specific reconstitution information please contact our Scientific Support Team.
General Info
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Alternative names
- C type lectin domain family 11 member A
- C type lectin superfamily member 3
- C-type lectin domain family 11 member A
see all -
Function
Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. -
Tissue specificity
Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. -
Sequence similarities
Contains 1 C-type lectin domain. -
Developmental stage
In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils. -
Post-translational
modificationsO-glycosylated. Probably sulfated on the O-glycans. -
Cellular localization
Cytoplasm. Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab9836 has not yet been referenced specifically in any publications.