Anti-Relaxin 2 antibody [2F1fred] (ab14330)

Overview

  • Product nameAnti-Relaxin 2 antibody [2F1fred]See all Relaxin 2 primary antibodies ...
  • Description
    Mouse monoclonal [2F1fred] to Relaxin 2
  • SpecificityThis antibody is specific for Human Relaxin 2 (signal peptide is cleaved from aa 1-24). There were no cross reactivities obtained with human Relaxin 1.
  • Tested applicationsELISA, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human Relaxin 2.
    Database link: P04090

Properties

Applications

Our Abpromise guarantee covers the use of ab14330 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
Flow Cyt Use at an assay dependent dilution.

Target

  • FunctionRelaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
  • Tissue specificityIsoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.
  • Sequence similaritiesBelongs to the insulin family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • FormProrelaxin 2 is Cleaved into the following 2 chains: 1.Relaxin B chain - aa 25-53. 2.Relaxin A chain - aa 162-185. The signal peptide is from aa 1-24.
  • Alternative names
    • H2 antibody
    • REL2_HUMAN antibody
    • Relaxin 2 antibody
    • Relaxin A chain antibody
    • Relaxin H2 antibody
    • RLN2 antibody
    • RLXH2 antibody
    see all

References for Anti-Relaxin 2 antibody [2F1fred] (ab14330)

ab14330 has not yet been referenced specifically in any publications.

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