Anti-Relaxin 2/RLN2 antibody (ab232707)
Key features and details
- Rabbit polyclonal to Relaxin 2/RLN2
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Relaxin 2/RLN2 antibody
See all Relaxin 2/RLN2 primary antibodies -
Description
Rabbit polyclonal to Relaxin 2/RLN2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee -
Immunogen
Recombinant full length protein (His-tag) corresponding to Human Relaxin 2/RLN2 aa 1 to the C-terminus. (Expressed in E.coli).
Database link: P04090 -
Positive control
- WB: Human placenta lysate; Recombinant human Relaxin 2/RLN2 protein. IHC-P: Human cerebrum, liver and liver cancer tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 44.12% PBS, 55.77% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab232707 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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WB |
Use a concentration of 1 - 5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 5 - 20 µg/ml. |
WB
Use a concentration of 1 - 5 µg/ml. |
Target
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Function
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. -
Tissue specificity
Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary. -
Sequence similarities
Belongs to the insulin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 449633 Chimpanzee
- Entrez Gene: 6013 Human
- Entrez Gene: 6019 Human
- Omim: 179740 Human
- SwissProt: P51455 Chimpanzee
- SwissProt: P04090 Human
- SwissProt: P04808 Human
- Unigene: 127032 Human
see all -
Form
Prorelaxin 2 is Cleaved into the following 2 chains: 1.Relaxin B chain - aa 25-53. 2.Relaxin A chain - aa 162-185. The signal peptide is from aa 1-24. -
Alternative names
- H2 antibody
- REL2_HUMAN antibody
- Relaxin 2 antibody
see all
Images
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Formalin-fixed, paraffin-embedded human liver tissue stained for Relaxin 2/RLN2 using ab232707 at 30 µg/ml in immunohistochemical analysis. DAB staining.
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Formalin-fixed, paraffin-embedded human cerebrum tissue stained for Relaxin 2/RLN2 using ab232707 at 30 µg/ml in immunohistochemical analysis. DAB staining.
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Formalin-fixed, paraffin-embedded human liver cancer tissue stained for Relaxin 2/RLN2 using ab232707 at 30 µg/ml in immunohistochemical analysis. DAB staining.
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Anti-Relaxin 2/RLN2 antibody (ab232707) at 2 µg/ml + Human placenta lysate
Secondary
HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution -
Anti-Relaxin 2/RLN2 antibody (ab232707) at 2 µg/ml + Recombinant human Relaxin 2/RLN2 protein
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab232707 has been referenced in 1 publication.
- Restucci B et al. Immunoexpression of Relaxin and Its Receptors in Stifle Joints of Dogs with Cranial Cruciate Ligament Disease. Animals (Basel) 12:N/A (2022). PubMed: 35405809