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Product Name 

Repulsive Guidance Molecule C antibody [Fery-1]

Product type 

Primary antibodies

Description 

Mouse monoclonal [Fery-1] to Repulsive Guidance Molecule C

Immunogen 

Recombinant fragment, corresponding to amino acids 36-398 of Human Repulsive Guidance Molecule C

Reacts with 
(species key)

Hu

Specificity 

ab54431 recognizes human Repulsive Guidance Molecule C.

Tested applications 
(see key)

Flow Cyt, IP


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
Flow Cyt: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cell Membrane

Research areas 

Developmental Biology >> Lineage specification >> Mesoderm
Signal Transduction >> Metabolism >> Vitamins / Minerals
Stem Cells >> Lineage Markers >> Mesoderm
Neuroscience >> Neurology process >> Neurogenesis

Relevance 

Mutations in Repulsive Guidance Molecule (also known as RGM-C; HJV; hemojuvelin; Hfe2) cause juvenile hemochromatosis, a severe iron overload disease. RGM-C gene expression has been characterized in the developing mouse and found to be exclusively expressed in all striated muscle and in the myocardium.

 

Repulsive Guidance Molecule C antibody [Fery-1] (ab54431)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

148738    (Human)

Omim

    

602390    (Human)

SwissProt

    

Q6ZVN8    (Human)

Unigene

    

632436    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

Fery-1

Isotype 

IgG2b

Purity 

Protein G purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: PBS

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified from concentrated hybridoma tissue cell culture supernatant. Greater than 95% pure by SDS-PAGE.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Repulsive Guidance Molecule C antibody [Fery-1] is on this datasheet. But please do contact us if you would like any reassurance!


 

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