Anti-Respiratory Syncytial Virus Nucleoprotein antibody [RSV1C3] (ab94806)
Key features and details
- Mouse monoclonal [RSV1C3] to Respiratory Syncytial Virus Nucleoprotein
- Suitable for: ELISA, IP, ICC/IF
- Reacts with: Respiratory syncytial virus
- Isotype: IgG2a
Overview
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Product name
Anti-Respiratory Syncytial Virus Nucleoprotein antibody [RSV1C3]
See all Respiratory Syncytial Virus Nucleoprotein primary antibodies -
Description
Mouse monoclonal [RSV1C3] to Respiratory Syncytial Virus Nucleoprotein -
Host species
Mouse -
Specificity
This antibody has broad specificity for Human Respiratory syncytial virus of both sub groups A and B. -
Tested applications
Suitable for: ELISA, IP, ICC/IFmore details -
Species reactivity
Reacts with: Respiratory syncytial virus -
Immunogen
Tissue, cells or virus corresponding to Respiratory Syncytial Virus Nucleoprotein. hRSV strain A2 infected HeLa cells
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General notes
Fusion partner: PS-NS/1-Ag4The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
RSV1C3 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab94806 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
Acetone fixed |
Notes |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. Acetone fixed |
Target
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Relevance
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. -
Cellular localization
Virus particle -
Alternative names
- Nucleoprotein antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (8)
ab94806 has been referenced in 8 publications.
- Liang W et al. Cyclophilin A Inhibits Human Respiratory Syncytial Virus (RSV) Replication by Binding to RSV-N through Its PPIase Activity. J Virol 95:e0056321 (2021). PubMed: 34011546
- Pei J et al. Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription. Cell Rep 37:109803 (2021). PubMed: 34644581
- Li J et al. Long Noncoding RNA NRAV Promotes Respiratory Syncytial Virus Replication by Targeting the MicroRNA miR-509-3p/Rab5c Axis To Regulate Vesicle Transportation. J Virol 94:N/A (2020). PubMed: 32102886
- Anderson DE et al. Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae. mBio 10:N/A (2019). PubMed: 31088929
- Lingemann M et al. The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells. PLoS Pathog 15:e1007963 (2019). PubMed: 31381610
- Challa S et al. Mechanism of action for respiratory syncytial virus inhibitor RSV604. Antimicrob Agents Chemother 59:1080-7 (2015). PubMed: 25451060
- Wei T et al. The eukaryotic elongation factor 1A is critical for genome replication of the paramyxovirus respiratory syncytial virus. PLoS One 9:e114447 (2014). PubMed: 25479059
- Jung J et al. Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation. Nucleic Acids Res : (2012). ICC/IF . PubMed: 22952158