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AbcamBiochemicals (Asc-726)

Resveratrol (ab120726)

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Overview

  • Product nameResveratrol
  • Description
    Antioxidant polyphenol with a multitude of biological activities
  • Biological descriptionPolyphenol found in grape skins and red wine. Displays a multitude of biological activities including anti-oxidant, anti-platelet, anti-tumour, anti-inflammatory and cardioprotective effects. Additionally shows anti-amyloidogenic and fibril-destabilising activities.
  • Purity> 99%

    • Properties

  • Chemical name5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol
  • Molecular Weight228.25
  • Chemical structureChemical Structure
  • Molecular formulaC14H12O3
  • CAS Number501-36-0
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • Source

    Synthetic

  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab120726 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent concentration.

    Resveratrol images

    • Functional Studies-Resveratrol(ab120726)
      Functional Studies-Resveratrol(ab120726)
      ab85555 staining PKM2 in HeLa cells treated with resveratrol (ab120726), by ICC/IF. Decrease in PKM2 expression correlates with increased concentration of resveratrol as described in literature.
      The cells were incubated at 37°C for 48h in media containing different concentrations of ab120726 (resveratrol) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab85555 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

    References for Resveratrol (ab120726)

    This product has been referenced in:
    • Csiszar A Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease. Ann N Y Acad Sci 1215:117-22 (2011). Read more (PubMed: 21261649) »
    • Granzotto A & Zatta P Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aß and Aß-metal complexes toxicity. PLoS One 6:e21565 (2011). Read more (PubMed: 21738712) »
    • Schneider Y  et al. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. Cancer Lett 158:85-91 (2000). Read more (PubMed: 10940513) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"