Overview

  • Product nameResveratrol
  • Description
    Antioxidant polyphenol with a multitude of biological activities
  • Biological descriptionPolyphenol found in grape skins and red wine. Displays a multitude of biological activities including antioxidant, antiplatelet, antitumour, anti-inflammatory and cardioprotective effects. Additionally, shows antiamyloidogenic and fibril-destabilising activities.
  • Purity> 99%

Properties

    Applications

    Our Abpromise guarantee covers the use of ab120726 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    Resveratrol images

    • ab85555 staining PKM2 in HeLa cells treated with resveratrol (ab120726), by ICC/IF. Decrease in PKM2 expression correlates with increased concentration of resveratrol as described in literature.
      The cells were incubated at 37°C for 48h in media containing different concentrations of ab120726 (resveratrol) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab85555 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

    References for Resveratrol (ab120726)

    This product has been referenced in:
    • Csiszar A Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease. Ann N Y Acad Sci 1215:117-22 (2011). Read more (PubMed: 21261649) »
    • Granzotto A & Zatta P Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aß and Aß-metal complexes toxicity. PLoS One 6:e21565 (2011). Read more (PubMed: 21738712) »
    • Schneider Y  et al. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. Cancer Lett 158:85-91 (2000). Read more (PubMed: 10940513) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"