Anti-RXRG antibody (ab15518)
Key features and details
- Rabbit polyclonal to RXRG
- Suitable for: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-P
- Reacts with: Mouse, Rat, Chicken, Hamster, Human
- Isotype: IgG
Overview
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Product name
Anti-RXRG antibody
See all RXRG primary antibodies -
Description
Rabbit polyclonal to RXRG -
Host species
Rabbit -
Specificity
From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.
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Tested applications
Suitable for: IHC-Fr, ICC/IF, IHC - Wholemount, WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat, Chicken, Hamster, Human -
Immunogen
Synthetic peptide within Mouse RXRG aa 1-100 (N terminal). The exact sequence is proprietary.
Database link: P28705 -
General notes
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15518 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr | (1) |
Use at an assay dependent concentration.
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ICC/IF | (2) |
Use at an assay dependent concentration.
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IHC - Wholemount | (1) |
Use at an assay dependent concentration.
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WB | (2) |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa.
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IHC-P | (4) |
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC - Wholemount
Use at an assay dependent concentration. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 51 kDa. |
IHC-P
1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. -
Sequence similarities
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
Domain
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 396231 Chicken
- Entrez Gene: 6258 Human
- Entrez Gene: 20183 Mouse
- Entrez Gene: 83574 Rat
- Omim: 180247 Human
- SwissProt: P28701 Chicken
- SwissProt: P48443 Human
- SwissProt: P28705 Mouse
see all -
Alternative names
- MGC109416 antibody
- NR2B3 antibody
- Nuclear receptor subfamily 2 group B member 3 antibody
see all
Images
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Anti-RXRG antibody (ab15518) at 1/25 dilution + NIH3T3 cell lysate
Predicted band size: 51 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted? -
ab15518 staining RXRG in breast carcinoma by Immunohistochemistry (FFPE-sections).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (15)
ab15518 has been referenced in 15 publications.
- Gao K et al. Qishen granules exerts cardioprotective effects on rats with heart failure via regulating fatty acid and glucose metabolism. Chin Med 15:21 (2020). PubMed: 32158496
- Thulasi Raman SN et al. Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus. Emerg Microbes Infect 9:2046-2060 (2020). PubMed: 32873194
- Wang GS et al. Expression and localization of retinoid receptors in the testis of normal and infertile men. Mol Reprod Dev 87:978-985 (2020). PubMed: 32770619
- Joseph C et al. Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer. Br J Cancer 121:776-785 (2019). PubMed: 31558802
- Aldunate EZ et al. Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. Sci Rep 9:2314 (2019). PubMed: 30783126