FunctionHas E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
Tissue specificityUbiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
PathwayProtein modification; protein ubiquitination.
Caspases 8 and 10 associated RING finger protein 2 antibody
caspases-8 and -10- associated RING finger protein 2 antibody
Caspases-8 and -10-associated RING finger protein 2 antibody
E3 ubiquitin protein ligase rififylin antibody
E3 ubiquitin-protein ligase rififylin antibody
FYVE RING finger protein Sakura antibody
FYVE-RING finger protein Sakura antibody
RING finger and FYVE like domain containing protein antibody
RING finger and FYVE-like domain-containing protein 1 antibody
RING finger protein 189 antibody
RING finger protein 34 like antibody
RING finger protein 34-like antibody
Anti-Rffl antibody images
Western blot - Rffl antibody (ab47994)
All lanes : Anti-Rffl antibody (ab47994) at 1/1000 dilution
Lane 1 : Empty vector 293T cell lysate with 5% BLOTTO,
0.1% Tween 20 in PBS Lane 2 : RNF34 transfected lysate with 5% BLOTTO,
0.1% Tween 20 in PBS Lane 3 : RFFL
transfected lysate with 5% BLOTTO,
0.1% Tween 20 in PBS
Lysates/proteins at 20 µl per lane.
Predicted band size : 41 kDa Observed band size : 41 kDa Additional bands at : 58 kDa. We are unsure as to the identity of these extra bands.
References for Anti-Rffl antibody (ab47994)
has not yet been referenced specifically in any publications.
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