AbcamBiochemicals

Ro 31-8220 mesylate (Bisindolylmaleimide IX) (ab120374)

Overview

  • Product nameRo 31-8220 mesylate (Bisindolylmaleimide IX)
  • Description
    Protein kinase inhibitor
  • Alternative names
    • Bisindolylmaleimide IX
  • Biological descriptionWidely used as a cell permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKCα, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα.
  • Purity> 98%

Properties

    References for Ro 31-8220 mesylate (Bisindolylmaleimide IX) (ab120374)

    This product has been referenced in:
    • Bain J  et al. The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297-315 (2007). Read more (PubMed: 17850214) »
    • Davis PD  et al. Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity. J Med Chem 35:994-1001 (1992). Read more (PubMed: 1552513) »
    • Dieter P & Fitzke E RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages. Biochem Biophys Res Commun 181:396-401 (1991). Read more (PubMed: 1958208) »

    See 0 Publications for this product

    Product Wall

    There are currently no Questions for ab120374.
    Please use the link above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"