Overview
Product nameRubella Virus E2 proteinSee all Rubella Virus E2 proteins and peptides ...
Protein descriptionRecombinant Rubella virus E2 immunodominant region (amino acids 31-105) with 6x His tag; Predicted MWt 9 kDa (UniProt P08563).
Uniprot accessionP08563
Molecular weight9kDa
Protein length75 amino acids
Expression hostE. coli
Properties
Purity> 80
% by SDS-PAGE
Purification notesab107948 is purified by Metal affinity chromatography.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: 1mM Hydrochloric acid
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab107948
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| WB |
WB: Use at an assay dependent dilution. |
| ELISA |
ELISA: Use at an assay dependent dilution. |
| SDS-PAGE |
SDS-PAGE: Use at an assay dependent dilution. |
Protein info
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Alternative names
E2E2 envelope glycoproteinE2 glycoproteinSpike glycoprotein E2
RelevanceRubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. The the two envelope glycoproteins E2 and E1 are found as a heterodimeric spike complex embedded in the lipid envelope. E2 envelope glycoprotein is responsible for viral attachment to target host cell, by binding to the cell receptor. Its transport to the plasma membrane depends on interaction with E1 protein.
Rubella or German measles is a mild disease in children and adults, but can cause devastating problems if it infects the fetus, especially if infection is in the first few weeks of pregnancy.
References for Rubella Virus E2 protein (ab107948)
ab107948
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
