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Products:Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Binding Proteins
Overview
Product name
Anti-S100 alpha 2 antibody
See all S100 alpha 2 products (5) ...
Description
Mouse monoclonal to S100 alpha 2
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length Human S100 alpha 2 (AAH02829) with a proprietary tag.
Positive control
A431 cell lysate. Tagged recombinant Human S100 alpha 2 protein.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Ascites
Concentration
Concentration information loading...
Purity
Ascites
Clonality
Monoclonal
Isotype
IgG2b
Light chain type
kappa
Research areas
Cell Biology >> Cell Cycle >> Cell differentiation
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Binding Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab89503 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Predicted molecular weight: 11 kDa.
ELISA: Use at an assay dependent dilution.
Target
Function
May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.
Tissue specificity
A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
Sequence similarities
Belongs to the S-100 family.
Contains 2 EF-hand domains.
Developmental stage
Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.
Target information above from: UniProt accessionP29034
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- S100 calcium binding protein A2 antibody
- CAN19 antibody
- MGC111539 antibody
see all
Database links
- Entrez Gene: 6273 Human
- Omim: 176993 Human
- SwissProt: P29034 Human
- Unigene: 516484 Human
Anti-S100 alpha 2 antibody images:
Western blot - S100 alpha 2 antibody (ab89503)
Anti-S100 alpha 2 antibody (ab89503) at 1/500 dilution + Tagged recombinant Human S100 alpha 2 protein at 0.2 µg
Predicted band size : 11 kDa
Observed band size : 37 kDa (why is the actual band size different from the predicted?)
Western blot against tagged recombinant protein immunogen. Predicted band size of immunogen is 37 kDa.
Western blot - S100 alpha 2 antibody (ab89503)
Anti-S100 alpha 2 antibody (ab89503) at 1/500 dilution + A431 cell lysate at 50 µg
Predicted band size : 11 kDa
Observed band size : 10 kDa (why is the actual band size different from the predicted?)
References for Anti-S100 alpha 2 antibody (ab89503)
ab89503 has not yet been referenced specifically in any publications.
Publishing research using ab89503? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"