Overview
- Product nameAnti-S100 beta antibodySee all S100 beta primary antibodies ...
- DescriptionRabbit polyclonal to S100 beta
- Tested applicationsWB, IP, ELISA more details
- Species reactivityReacts with: Human
- Immunogen
Full length native S100 beta purified from human plasma
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.50
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading... - PurityProtein G purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab110979 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: Use at an assay dependent dilution. Predicted molecular weight: 11 kDa. |
| IP | IP: Use at an assay dependent dilution. |
| ELISA | ELISA: Use at an assay dependent dilution. |
Target
- FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
- Tissue specificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
- Sequence similaritiesBelongs to the S-101 family.
Contains 2 EF-hand domains. - Cellular localizationCytoplasm. Nucleus.
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Database links
- Entrez Gene: 6285 Human
- Omim: 176990 Human
- SwissProt: P04271 Human
- Unigene: 422181 Human
Target information above from: UniProt accession
P04271
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- NEF antibodyProtein S100 B antibodyProtein S100-B antibody
- S 100 calcium binding protein beta chain antibodyS 100 protein beta chain antibodyS-100 protein beta chain antibodyS-100 protein subunit beta antibodyS100 antibodyS100 calcium binding protein beta (neural) antibodyS100 calcium-binding protein B antibodyS100 protein beta chain antibodyS100B antibodyS100B_HUMAN antibodyS100beta antibody
see all
References for Anti-S100 beta antibody (ab110979)
ab110979 has not yet been referenced specifically in any publications.
