Overview
Product nameS100 beta peptideSee all S100 beta proteins and peptides ...
Protein descriptionSynthetic peptide derived from within residues 50 to the C-terminus of Rat S100 beta.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41548 - S100 beta antibody.
Protein length92 amino acids
Properties
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferInformation available upon request.
Concentration information loading...
Research Areas
Applications
Application notesThis peptide can be used with studies using ab41548.
Protein info
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Alternative names
Protein S100-BS 100 calcium binding protein beta chainS 100 protein beta chainS 100 protein beta subunitS-100 protein beta chainS-100 protein subunit betaS100S100 calcium binding protein BS100 calcium binding protein beta (neural)S100 calcium binding protein beta chainS100 calcium-binding protein BS100 protein beta chainS100BS100B_HUMANS100beta
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FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Tissue specificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Sequence similaritiesBelongs to the S-101 family.
Contains 2 EF-hand domains.
Cellular localizationCytoplasm. Nucleus.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"