S100A5 protein (ab64453)

Product Name 

S100A5 protein

Product type 

Proteins and Peptides

Peptide 

Recombinant full length Human S100A5, Swiss-ProtP33763. M.Wt 22 kDa (dimer).

Tested applications 
(see key)

SDS-PAGE

Application notes 
(see key)

Recommended dilutions
SDS-PAGE: Use at an assay dependent dilution.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Binding Proteins
Neuroscience >> Neurotransmission >> Calcium Signaling >> Calcium Binding Proteins

Relevance 

S100A5 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.

Purity 

>90% by SDS-PAGE

Storage buffer 

Preservative: None
Constituents: 20mM MES, 100mM Sodium chloride, pH 6.5

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at -20°C, Stable for 6 months at -20°C

Notes 

This product can be concentrated to a maximum of 1.5mM (dimer), and avoid precipitation.

Expression system 

E. coli

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