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Product Name
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S100A9 antibody [NO.134]
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See all S100A9 antibodies (10)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [NO.134] to S100A9
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Immunogen
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Full length native protein (purified)
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, sELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at a concentration of 1 - 10 µg/ml.
sELISA: Can be paired for ELISA with Mouse monoclonal [NO.19] to Macrophage L1 protein Calprotectin (ab50138). b50143 can be used as a capture antibody in a human Calprotectin ELISA in combination with monoclonal antibody ab50138. Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasm; Nucleus (not nucleolus)
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Research areas
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Cancer >> Tumor biomarkers >> Other
Cancer >> Drug resistance >> MRP-related proteins
Cell Biology >> Cell Cycle >> Cell differentiation
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Binding Proteins
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Relevance
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S100A9 is a member of the S100 family of proteins. S100A9, together with S100A8 forms a heterodimeric protein complex, Calprotectin, which is a major calcium- and zinc-binding protein in the cytosol of neutrophils, monocytes, and keratinocytes. Complexes of S100A8 and S100A9 are the physiologically relevant forms of these proteins.
S100A9 may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis.
Its expression and potential cytokine-like function in inflammation and in cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer.
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S100A9 antibody [NO.134] (ab50143) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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NO.134
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.15mM PBS, pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this S100A9 antibody [NO.134] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for S100A9 antibody [NO.134] (ab50143)
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This product has been used in:
Reyes L et al. Complicated urinary tract infection is associated with uroepithelial expression of proinflammatory protein S100A8. Infect Immun 77:4265-74 (2009). PubMed: 19667050
If you publish research using ab50143 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to S100A9
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S100A9 antibody [NO.134] - more information
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