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Products:Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
Overview
Product name
Anti-SAMSN1 antibody
See all SAMSN1 products (4) ...
Description
Goat polyclonal to SAMSN1
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide: IRLDTLSASLGRS-C (Human) Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody may be recognising one particular isoform.
IRLDTLSASL GRS-C
Positive control
Jurkat lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
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Western blot - Anti-SAMSN1 antibody (ab21206)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab21206 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
- 1 Image
WB
Application notes
ELISA: Use at an assay dependent dilution. The antibody detection limit dilution is 1:64,000 in a peptide ELISA.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 48 kDa in Jurkat cell lysates (predicted molecular weight: 42 kDa). The observed size is consistent with observations with competing products.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.
Alternative names
- SAM domain, SH3 domain and nuclear localization signals protein 1 antibody
- HACS1 antibody
- hematopoietic adaptor containing SH3 and SAM domains 1 antibody
see all
Database links
- Entrez Gene: 64092 Human
- NCBI: 48762709 Human
- Omim: 607978 Human
- SwissProt: Q9NSI8 Human
- Unigene: 473341 Human
Anti-SAMSN1 antibody images:
Western blot - Anti-SAMSN1 antibody (ab21206)
Predicted band size : 42 kDa
ab21206 (1 ug/ml) western blot detection of SAMSN1 from Jurkat cell lysate.
References for Anti-SAMSN1 antibody (ab21206)
ab21206 has not yet been referenced specifically in any publications.
Publishing research using ab21206? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"