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Products:Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
Overview
Product name
Anti-SAMSN1 antibody
See all SAMSN1 products (4) ...
Description
Rabbit polyclonal to SAMSN1
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow, Dog
Immunogen
Synthetic peptide: YVDVISEEEA APKKIKANRR SNSKKSKTLQ EFLERIHLQE YTSTLLLNGY , corresponding to amino acids 218-267 of Human SAMSN1
YVDVISEEEA APKKIKANRR SNSKKSKTLQ EFLERIHLQE YTSTLLLNGY
Positive control
Human fetal muscle lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
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Western blot - SAMSN1 antibody (ab76389)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab76389 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
ELISA
Application notes
ELISA: Use at an assay dependent dilution. Titre using peptide based assay: 1/62500.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung. SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.
Alternative names
- SAM domain, SH3 domain and nuclear localization signals protein 1 antibody
- HACS1 antibody
- hematopoietic adaptor containing SH3 and SAM domains 1 antibody
see all
Database links
- Entrez Gene: 64092 Human
- Entrez Gene: 67742 Mouse
- Entrez Gene: 170637 Rat
- NCBI: 48762709 Human
- Omim: 607978 Human
- SwissProt: Q9NSI8 Human
- SwissProt: P57725 Mouse
- Unigene: 473341 Human
see all
Anti-SAMSN1 antibody images:
Western blot - SAMSN1 antibody (ab76389)
Anti-SAMSN1 antibody (ab76389) at 1 µg/ml + Human fetal muscle lysate at 10 µg
Secondary
HRP-conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 42 kDa
Observed band size : 39 kDa (why is the actual band size different from the predicted?)
Gel concentration: 12%
References for Anti-SAMSN1 antibody (ab76389)
ab76389 has not yet been referenced specifically in any publications.
Publishing research using ab76389? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"