SAMSN1 peptide (ab45611)

Product Name 

SAMSN1 peptide

Product type 

Proteins and Peptides

Peptide 

Synthetic N terminal peptide: IRLDTLSASLGRS-C (Human)

This peptide was used as an immunogen for ab21206 - SAMSN1 antibody.

Please note that this sequence is present in NP_071419.2 (and in
AAK07746) but is no longer present in the latest reference sequence
(NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI.
BLAST 'IRLDTLSASLGRS-C' with or

Research areas 

Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
Signal Transduction >> Adapters >> Cytoplasmic

Relevance 

SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It also contains several predicted consensus nuclear localization signals and a tyrosine kinase phosphorylation motif. Northern blot analysis has revealed expression of a 2.2kb SAMSN1 transcript in human immune tissues and hematopoietic cell types including normal bone marrow, acute myeloid leukemia, and multiple myeloma; low-level expression was seen in other tissues such as heart, brain, placenta, and lung.
SAMSN1 has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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