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- Primary antibodies
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Product name
SAP102 peptide
See all SAP102 products (2) ...
Protein description
Synthetic peptide derived from within residues 100 - 200 of Human SAP102. (Note: the amino acid sequence is proprietary).
Protein length
817 amino acids
Expression host
CHO
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Neuroscience >> Cell Type Marker >> Neuron marker >> Dendrite marker
Neuroscience >> Neurotransmission >> Intracellular Signaling >> Adapters
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Western blot - SAP102 peptide (ab12417)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab12417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking
Application notes
BL: Use at a concentration of 1-3 µg/ml.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Involvement in disease
Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Sequence similarities
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain.
Target information above from: UniProt accessionQ92796
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
SAP102 peptide images:
Western blot - SAP102 peptide (ab12417)
Lane 1 : Anti-SAP102 antibody (ab12086) at 0.3 µg/ml Chris Anderson, Wellcome Trust Sanger Institute, United Kingdom
Lane 2 : Anti-SAP102 antibody (ab12086) at 1 µg/ml
Lanes 3 - 4 : Anti-SAP102 antibody (ab12086) at 3 µg/ml
Lane 1 : As above
Lane 2 : As above
Lane 3 : As above
Lane 4 :
Performed under reducing conditions.
Observed band size : 100,110 kDa (why is the actual band size different from the predicted?)
Additional bands at : 80 kDa,85 kDa. We are unsure as to the identity of these extra bands.
Exposure time : 10 seconds
References for SAP102 peptide (ab12417)
ab12417 has not yet been referenced specifically in any publications.
Publishing research using ab12417? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"