Overview

  • Product name
  • Description
    Rabbit polyclonal to SAP130
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    A synthetic peptide corresponding to a region between amino acids 998-1048 of Human SAP130 (NP_078821.2).

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab114978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
    • Tissue specificity
      Expressed in various cancer cell ines.
    • Sequence similarities
      Belongs to the SAP130 family.
    • Domain
      The N-terminus may interact with a transcriptional coactivator.
      The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.
    • Post-translational
      modifications
      Acetylated.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 130 kDa Sin3-associated polypeptide antibody
      • FLJ12761 antibody
      • Histone deacetylase complex subunit SAP130 antibody
      • KIAA0017 antibody
      • mSin3A associated protein 130 antibody
      • Pre mRNA splicing factor SF3b 130 kDa subunit antibody
      • RSE1 antibody
      • SAP 130 antibody
      • Sap130 antibody
      • SF3b 130 antibody
      • SF3b130 antibody
      • SF3B3 antibody
      • Sin3-associated polypeptide p130 antibody
      • Sin3A associated protein 130kDa antibody
      • Sin3A associated protein antibody
      • SP130_HUMAN antibody
      • Spliceosome associated protein 130 antibody
      • Splicing factor 3b subunit 3 130kDa antibody
      • Splicing factor 3b subunit 3 antibody
      • STAF 130 antibody
      • STAF130 antibody
      see all

    Images

    • ab114978, used for IP at 3 µg/mg lysate,staining SAP130 in HeLa whole cell lysate (1 µg for IP, 20% of IP loaded).

      Detection: Chemiluminescence with an exposure time of 10 seconds.

    References

    ab114978 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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