Anti-SAP130 antibody (ab114978)

Overview

• Product nameAnti-SAP130 antibodySee all SAP130 primary antibodies ...
• Description
  Rabbit polyclonal to SAP130
• Tested applicationsIP more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  A synthetic peptide corresponding to a region between amino acids 998-1048 of Human SAP130 (NP_078821.2).

• Positive controlHeLa whole cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium azide
  Constituent: 99% Tris citrate/phosphate
  Note: pH 7 to 8
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab114978 is affinity purified using an epitope specific to SAP130 immobilized on solid support
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Epigenetics and Nuclear Signaling
  • Chromatin Modifying Enzymes
  • Acetylation

  • Epigenetics and Nuclear Signaling
  • Chromatin Binding Proteins
  • DNA / RNA binding

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • RNA Processing

Applications

Target

• FunctionActs as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
• Tissue specificityExpressed in various cancer cell ines.
• Sequence similaritiesBelongs to the SAP130 family.
• DomainThe N-terminus may interact with a transcriptional coactivator.
  The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.
• Post-translational
  modificationsAcetylated.
• Cellular localizationNucleus.

Target information above from: UniProt accession Q9H0E3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 79595 Human
  • Omim: 609697 Human
  • SwissProt: Q15393 Human
  • SwissProt: Q9H0E3 Human
  • Unigene: 32995 Human

• Alternative names
  130 kDa Sin3-associated polypeptide antibodyFLJ12761 antibodyHistone deacetylase complex subunit SAP130 antibody

  KIAA0017 antibodymSin3A associated protein 130 antibodyPre mRNA splicing factor SF3b 130 kDa subunit antibodyRSE1 antibodySAP 130 antibodySap130 antibodySF3b 130 antibodySF3b130 antibodySF3B3 antibodySin3-associated polypeptide p130 antibodySin3A associated protein 130kDa antibodySin3A associated protein antibodySP130_HUMAN antibodySpliceosome associated protein 130 antibodySplicing factor 3b subunit 3 130kDa antibodySplicing factor 3b subunit 3 antibodySTAF 130 antibodySTAF130 antibody

  see all

Anti-SAP130 antibody images

• 

  Immunoprecipitation - Anti-SAP130 antibody (ab114978)
  ab114978, used for IP at 3 µg/mg lysate,staining SAP130 in HeLa whole cell lysate (1 µg for IP, 20% of IP loaded).
  
  Detection: Chemiluminescence with an exposure time of 10 seconds.