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SAP130 peptide (1204-1217) (ab22952)

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Overview

Product name

SAP130 peptide (1204-1217)

Protein description

Synthetic peptide: C-VSKKLEDIRTRYAF, corresponding to amino acids 1204-1217 of Human SAP130.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Concentration

Concentration information loading...

Sequence

C-VSKKLEDI RTRYAF

Applications

Application notes

This peptide can be used with studies using ab3608.

Protein info

Function

Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.

Tissue specificity

Expressed in various cancer cell ines.

Sequence similarities

Belongs to the SAP130 family.

Domain

The N-terminus may interact with a transcriptional coactivator.
The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.

Post-translational
modifications

Acetylated.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ9H0E3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for SAP130 peptide (1204-1217) (ab22952)

ab22952 has not yet been referenced specifically in any publications.

Publishing research using ab22952? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"