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Products:Epigenetics and Nuclear Signaling >> RNAi >> Argonaute and Piwi
Overview
Product name
SAP18 peptide
See all SAP18 products (2) ...
Protein description
Synthetic peptide derived from within residues 1 - 100 of Human SAP18. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab31748 - .
Protein length
153 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Epigenetics and Nuclear Signaling >> RNAi >> Argonaute and Piwi
Applications
Show applications key
Our Abpromise guarantee covers the use of ab30465 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking
Application notes
BL: Use at a concentration of 1 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.
Tissue specificity
Ubiquitous.
Sequence similarities
Belongs to the SAP18 family.
Cellular localization
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.
Target information above from: UniProt accessionO00422
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for SAP18 peptide (ab30465)
ab30465 has not yet been referenced specifically in any publications.
Publishing research using ab30465? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"