Overview
Product nameSARS M proteinSee all SARS M proteins and peptides ...
Protein descriptionRecombinant fragment: SARS Associated Coronavirus M recombinant protein fragment containing the immunodominant regions (amino acids 182-221).
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notesSepharose derived purification.
Biological activityImmunoreactive with sera of SARS infected individuals.
FormLiquid
Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 50% Glycerol, 60mM Sodium chloride, 50mM Tris HCl
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab43028
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| ELISA |
|
| WB |
|
Application notesELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Excellent antigen for detection of SARS with minimal specificity problems.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
RelevanceA novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. The M protein (Membrane protein, Matrix protein) is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein and the nucleocapsid protein.
Coronaviruses have four important viral genes with different structural proteins: a spike glycoprotein (S), a small envelope protein (E), a matrix glycoprotein (M), and a nucleocapsid protein (N).
Cellular localizationviral envelope
References for SARS M protein (ab43028)
ab43028
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
