Anti-SARS Nucleocapsid Protein antibody (ab22163)

Overview

  • Product nameAnti-SARS Nucleocapsid Protein antibody
    See all SARS Nucleocapsid Protein primary antibodies
  • Description
    Rabbit polyclonal to SARS Nucleocapsid Protein
  • Specificityab22163 reacts with SARS-Nucleocapsid protein.
  • Tested applicationsWB, ELISAmore details
  • Immunogen

    Synthetic peptide:

    GPTDSTDNNQNGGRN

    , corresponding to N terminal amino acids 20-34 of putative human coronavirus SARS nucleocapsid protein

  • Positive control
    • Transfected mouse melanoma cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium azide
    Constituents: PBS, 0.2% Gelatin
  • Concentration information loading...
  • PurityIgG fraction
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab22163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/2000. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
ELISA 1/100 - 1/2000.

Target

  • RelevanceSevere Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus (SARS-CoV). SARS is caused by a human coronavirus, which are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
  • Cellular localizationInside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.
  • Alternative names
    • N antibody
    • N structural protein antibody
    • NC antibody
    • Nucleocapsid protein antibody
    • Nucleoprotein antibody
    • Protein N antibody
    • SARS coronavirus N protein antibody
    • SARS CoV antibody
    • SARSCoV antibody
    • Severe acute respiratory syndrome antibody
    see all

Anti-SARS Nucleocapsid Protein antibody images

  • All lanes : Anti-SARS Nucleocapsid Protein antibody (ab22163) at 1/2000 dilution

    Lane 1 : transfected mouse melanoma cell lysate
    Lane 2 : untransfected cell lysate


    Predicted band size : 46 kDa
    Observed band size : 46 kDa

References for Anti-SARS Nucleocapsid Protein antibody (ab22163)

ab22163 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"