Anti-SARS Nucleocapsid Protein antibody (ab22163)

Overview

• Product nameAnti-SARS Nucleocapsid Protein antibodySee all SARS Nucleocapsid Protein primary antibodies ...
• Description
  Rabbit polyclonal to SARS Nucleocapsid Protein
• Specificityab22163 reacts with SARS-Nucleocapsid protein.
• Tested applicationsWB, ELISA more details
• Immunogen

  Synthetic peptide: GPTDSTDNNQNGGRN, corresponding to N terminal amino acids 20-34 of putative human coronavirus SARS nucleocapsid protein

  Run BLAST with Run BLAST with
• Positive controlTransfected mouse melanoma cell lysate

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.05% Sodium Azide
  Constituents: 0.2% Gelatin, PBS
• Concentration information loading...
• PurityIgG fraction
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Microbiology
  • Organism
  • Virus
  • RNA Virus
  • ssRNA positive strand virus
  • SARS Coronavirus

Applications

Target

• RelevanceSevere Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus (SARS-CoV). SARS is caused by a human coronavirus, which are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
• Cellular localizationInside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.

• Alternative names
  N antibodyN structural protein antibodyNC antibody

  Nucleocapsid protein antibodyNucleoprotein antibodyProtein N antibodySARS coronavirus N protein antibodySARS CoV antibodySARSCoV antibodySevere acute respiratory syndrome antibody

  see all

Anti-SARS Nucleocapsid Protein antibody images

• 

  Western blot - SARS Nucleocapsid Protein antibody (ab22163)
  All lanes : Anti-SARS Nucleocapsid Protein antibody (ab22163) at 1/2000 dilution
  
  Lane 1 : transfected mouse melanoma cell lysate
  Lane 2 : untransfected cell lysate
  
  
  Predicted band size : 46 kDa
  Observed band size : 46 kDa