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SB 203580 hydrochloride

Product code: ab120235 (formerly Asc-235)

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Overview

Product name

SB 203580 hydrochloride

Description

p38 MAP kinase inhibitor; water soluble

Biological description

Water soluble, cell permeable p38 MAP kinase inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1 , RIP2 c-Raf and GSK3.

Purity

> 99%

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Properties

Chemical name

4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine hydrochloride

Molecular Weight

413.90

Chemical structure

Chemical Structure

Molecular formula

C21H16FN3OS.HCl

CAS Number

869185-85-3

Solubility

Soluble in water to 5 mM (at room temperature) and in water to 25 mM (with warming)

Storage instructions

Store at +4°C (desiccating conditions). Do not freeze.

Research areas

Biochemicals >> Pharmacology >> Enzymes >> Kinase >> MAP kinase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Product Range >> Just Add Water

References for SB 203580 hydrochloride (ab120235)

This product has been referenced in:

See all 3 publications for this product

Publishing research using ab120235? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"